研究業績 | 京都大学大学院農学研究科食品生物科学専攻生物機能変換学分野

研究業績 (Publications)

2017年

原著論文

  1. Sayoko Oiki, Reiko Kamochi, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto. Alternative substrate-bound conformation of bacterial solute-binding protein involved in the import of mammalian host glycosaminoglycans.
    Sci. Rep., 7(1), Article number: 17005 (2017).
  2. Kanate Temtrirath, Kenji Okumura, Yukie Maruyama, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto. Binding mode of metal ions to the bacterial iron import protein EfeO.
    Biochem. Biophys. Res. Commun., 493(2), 1095-1101 (2017).
  3. Ai Kaneko, Kasumi Uenishi, Yukie Maruyama, Nobuhiro Mizuno, Seiki Baba, Takashi Kumasaka, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto. A solute-binding protein in the closed conformation induces ATP hydrolysis in a bacterial ABC transporter involved in the import of alginate. J. Biol. Chem., 292(38), 15681-15690 (2017).
  4. Fumiya Matsuoka, Makoto Hirayama, Takayuki Kashihara, Hideki Tanaka, Wataru Hashimoto, Kousaku Murata, and Shigeyuki Kawai. Crucial role of 4-deoxy-L-erythro-5-hexoseulose uronate reductase for alginate utilization revealed by adaptive evolution in engineered Saccharomyces cerevisiae. Sci. Rep., 7(1), Article number: 4206 (2017).
  5. Sayoko Oiki, Bunzo Mikami, Yukie Maruyama, Kousaku Murata, and Wataru Hashimoto: A bacterial ABC transporter enables import of mammalian host glycosaminoglycans. Sci. Rep., 7(1), Article number: 1069 (2017).
  6. Takumi Yamashiro, Kousaku Murata, and Shigeyuki Kawai: Extremely high intracellular concentration of glucose-6-phosphate and NAD(H) in Deinococcus radiodurans. Extremophiles, 21(2), 399-407 (2017).

総説・その他

  1. 老木紗予子、中道優介、丸山如江、村田幸作、橋本 渉. 病原細菌による宿主細胞外グリコサミノグリカンの断片化・輸送・分解・代謝に関わる分子機構.
    生化学, 89(6),866-871 (2017).
  2. 橋本 渉. 微生物がつくる多様な増粘安定剤.
    食と微生物の事典(北本勝ひこ、春田伸、丸山潤一、後藤慶一、尾花望、斎藤勝晴 編), 朝倉書店, pp122-125 (2017).
  3. Wataru Hashimoto. Studies on novel enzymes for degradation of fragmented glycosaminoglycans.
    Glycoscience 2013-2017 In Commemoration of the 25th Anniversary of Mizutani Foundation for Glycoscience, pp96-97 (2017).
  4. 橋本 渉. 宿主細胞外マトリックスを介したプロバイオティクスとヒト腸管との相互作用.
    メールマガジン「Nutrition News」 Vol. 154 (2017).
  5. 河井重幸、村田幸作: 酵母による海藻(褐藻、紅藻)糖質発酵へ向けて.
    酵素工学ニュース, 77(4), 12-16 (2017).
  6. 河井重幸、村田幸作: ミトコンドリアNADキナーゼ遺伝子(NADK2)欠損症の症例報告.
    ビタミン, 91(3), 204-206 (2017).
  7. 河井重幸、村田幸作: 酵母による褐藻糖質からのエタノール生産.
    バイオサイエンスとインダストリー, 75(1), 42-43 (2017).
  8. Kenji Okumura, Sayoko Oiki, Hisamu Iwase, Masahiro Sato, Yukie Maruyama, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto. Crystal structure of alginate/metal-binding protein Algp7 from Sphingomonas strain sp. A1 at higher resolution.
    SPring-8 User Experiment Report, 2017B2592 (2017).

2016年

原著論文

  1. Masahiro Kobayashi, Hidenori Konishi, Yukie Maruyama, Kousaku Murata, and Wataru Hashimoto: Lateral-typed flagellin responsible for formation of a polar flagellum but not of lateral flagella in Sphingomonas sp. strain A1.
    Microbiology, 162(12), 2042-2052 (2016).
  2. Yusuke Nakamichi, Sayoko Oiki, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto: Conformational change in the active site of Streptococcal unsaturated glucuronyl hydrolase through site-directed mutagenesis at Asp-115.
    Protein J., 35(4), 300-309 (2016).
  3. Ryuichi Takase, Yukie Maruyama, Sayoko Oiki, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto: Structural determinants in bacterial 2-keto-3-deoxy-D-gluconate dehydrogenase KduD for dual-coenzyme specificity.
    Proteins, 84(7), 934-947 (2016).
  4. Makoto Hirayama, Wataru Hashimoto, Kousaku Murata, and Shigeyuki Kawai: Comparative characterization of three bacterial exo-type alginate lyases.
    Int. J. Biol. Macromol., 86(5), 519-524 (2016).

総説・その他

  1. Sayoko Oiki, Reiko Kamochi, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto: Conformational change of bacterial solute-binding protein involved in import of glycosaminoglycans.
    SPring-8 User Experiment Report, 2016B2574 (2016).
  2. 橋本 渉、丸山如江、伊藤貴文、髙瀬隆一、村田幸作: ヘテロ多糖の輸送にかかわる細菌由来超分子の構造基盤.
    化学と生物, 4(12), 885-891 (2016).
  3. Haruka Sugiura, Sayoko Oiki, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto: Crystal structure of Bacillus subtilis solute-binding protein YesO for sugar import.
    SPring-8 User Experiment Report, 2016A2574 (2016).
  4. Shigeyuki Kawai, and Kousaku Murata: Biofuel production based on carbohydrates from both brown and red macroalgae: Recent developments in key biotechnologies.
    Int. J. Mol. Sci., 17 (2), doi: 10.3390/ijms17020145 (2016).
  5. 河井重幸: 海洋バイオマスを原料とした出芽酵母によるエタノールの生産.
    化学工業 67(1), 15-19 (2016).
  6. 河井重幸: ヒトのミトコンドリアにおけるNADP+合成酵素のリン酸化によるNADP+合成制御の生理的役割.
    日本応用酵素協会誌 50, 29-30 (2016).
  7. 河井重幸: 第5章 代謝 1. 代謝と化学エネルギー.
    応用微生物学 第3版(横田 篤,大西康夫,小川 順 編)文永堂出版,東京,85-87 (2016).

2015年

原著論文

  1. Yukie Maruyama, Takafumi Itoh, Ai Kaneko, Yu Nishitani, Bunzo Mikami, Wataru Hashimoto, and Kousaku Murata: Structure of a bacterial ABC transporter involved in the import of the acidic polysaccharide alginate.
    Structure, 23(9), 1643-1654 (2015).
  2. Yukie Maruyama, Masahiro Kobayashi, Kousaku Murata, and Wataru Hashimoto: Formation of a single polar flagellum by lateral and polar bacterial flagellar gene sets in Sphingomonas sp. strain A1.
    Microbiology, 161(8), 1552-1560 (2015).
  3. Fuminori Yoneyama, Mayumi Yamamoto, Wataru Hashimoto, and Kousaku Murata: Production of polyhydroxybutyrate and alginate from glycerol by Azotobacter vinelandii under nitrogen-free conditions.
    Bioengineered, 6(4), 209-217 (2015).
  4. Wataru Hashimoto, Akihito Ochiai, Chang Soo Hong, Kousaku Murata, and Ananda M. Chakrabarty: Structural studies on Laz, a promiscuous anticancer Neisserial protein.
    Bioengineered, 6(3), 141-148 (2015).
  5. Yukie Maruyama, Sayoko Oiki, Ryuichi Takase, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto: Metabolic fate of unsaturated glucuronic/iduronic acids from glycosaminoglycans: Molecular identification and structure determination of streptococcal isomerase and dehydrogenase.
    J. Biol. Chem., 290(10), 6281-6292 (2015).
  6. Kanate Temtrirath, Kousaku Murata, and Wataru Hashimoto: Structural insights into alginate binding by bacterial cell-surface protein.
    Carbohydr. Res., 404, 39-45 (2015).
  7. Yutaka Kawabata, Kousaku Murata, and Shigeyuki Kawai: Significance of Ser-188 in human mitochondrial NAD kinase as determined by phosphomimetic and phosphoresistant amino-acid substitutions.
    Biochem. Biophys. Res. Commun., 468, 691-695 (2015).
  8. Shiori Yoshida, Hideki Tanaka, Makoto Hirayama, Kousaku Murata, and Shigeyuki Kawai: Production of pyruvate from mannitol by mannitol-assimilating pyruvate decarboxylase-negative Saccharomyces cerevisiae.
    Bioengineered, 6(6), 347-350 (2015).
  9. Moeko Chujo, Shiori Yoshida, Anri Ota, Kousaku Murata, and Shigeyuki Kawai: Acquisition of the ability to assimilate mannitol by Saccharomyces cerevisiae through dysfunction of the general corepressor Tup1–Cyc8.
    Appl. Environ. Microbiol., 81(1), 9-16 (2015). (M. Chujo and S. Kawai equally contributed to this work.)

総説・その他

  1. Sayoko Oiki, Kasumi Uenishi, Yukie Maruyama, Bunzo Mikami, Kousaku Murata, and Wataru Hashimoto: Crystal structure of Streptobacillus solute-binding protein involved in import of glycosaminoglycans.
    SPring-8 User Experiment Report, 2015B2058 (2015).
  2. Shigeyuki Kawai, and Kousaku Murata: Transformation of intact cells of Saccharomyces cerevisiae: original and modified lithium methods, and possible underlying mechanism.
    Genetic transformation systems in fungi, Volume 1, (Marco A. van den Berg, Karunakaran Maruthachalam eds.), Springer, Switzerland, 187-192 (2015).
  3. Shigeyuki Kawai, and Kousaku Murata: Transformation of Saccharomyces cerevisiae: spheroplast method.
    Genetic transformation systems in fungi, Volume 1, (Marco A. van den Berg, Karunakaran Maruthachalam eds.), Springer, Switzerland, 61-63 (2015).